Advantage Multi

Advantage     A topical monthly prevention that is applied on the skin between the shoulder blades (in an area that cannot be licked off). This product is used in both dogs and cats.
    Cats: Advantage Multi can be applied to those kittens that weigh 3 pounds or more or are at least 9 weeks old. It contains two main ingredients, moxidectin and imidacloprid, which are used to prevent heartworm infections, fleas, roundworms, hookworms, and ear mites. Moxidectin is used to prevent heartworm infestations, which are deadly when they occur in cats. This component is also used to treat and prevent roundworm, hookworm, and ear mite infections. These parasites can be spread to other cats and potentially humans (hookworms and roundworms). Imidacloprid is used to treat and control adult fleas as well as several larval stages.
    Dogs: Advantage Multi can be applied to those puppies weighing at least 3 pounds or are 7 weeks old. Moxidectin is used to prevent heartworm infestations as well as roundworms, hookworms, and whipworms. New information has recently been released that Advantage Multi treats and control sarcoptic mange, a skin mite that causes extreme itching and hairloss, and can be spread to other animals. As with cats, imidacloprid kills adult fleas and treats infestations by controlling several larval stages.
    For both dogs and cats, within 12 hours of application, 98-100% of adult fleas biting pets are killed. Fleas do not need to bite the pet in order to receive a lethal dose, so this product may reduce the incidence of flea allergy dermatitis.

Frontline Plus

Frontline     This monthly topical product is used in dogs and cats to kill adult fleas, ticks, flea eggs and larvae. It contains two main ingredients: fipronil and methoprene. Fipronil kills adult fleas and ticks within 12 hours of application. Methoprene kills flea eggs and larvae, thereby preventing them from developing into adults. The product is stored in pets' oil glands of skin. It will then self distribute continuously for 1 month to the hair and skin. As a result, fleas and ticks do not need to bite the pet in order to get the product – it will kill them if they just come in contact with the haircoat. Since fleas rise to the top of the haircoat as they die, it is normal to see more fleas after first applying Frontline.
    If a pet does have fleas, it is necessary to treat all in contact animals for at least 3 months (though we recommend year round) in order to eliminate the young fleas in the home environment. Do not apply the product 48 hours before or after swimming or bathing, as this can decrease the efficacy of the product. Puppies and kittens can begin this prevention as early as 8 weeks of age.
    Since this product does not offer any heartworm or intestinal parasite protection, it is necessary to add on another type of prevention (such as Heartgard) to protect from those dangerous parasites.


Heartgard     This monthly oral prevention is used in dogs and contains two main ingredients: ivermectin and pyrantel. Ivermectin is a compound that prevents heartworm infections by killing immature worms. This component does not continuously kills worms, but rather kills those immature worms that were introduced in the last 30 days and prevents them from developing into adults. This is important because while there may not be any clinical signs associated with a heartworm infection of immature worms, the adult worms cause heart failure and pulmonary emboli. As with any heartworm prevention, dogs need to be started on it within 1 month of a negative test. If there have been missed doses, it would be necessary to re-test. This is because missing doses can allow the worms to mature, and preventative medications are not effective in treating mature worms. Some dog breeds (such as Collies and Shelties) can be genetically sensitive to the ivermectin, so we would recommend either a different product or testing to make sure they do not have the gene mutation.
    The other ingredient is pyrantel, which is used to treat and control roundworms and hookworms, two common intestinal parasites. These worms can be transmitted from nursing, the placenta, or coming into contact with infected feces. They can cause diarrhea, weight loss, vomiting, weakness, and loss of appetite.
    Heartgard is safe to use in dogs beginning at 6 weeks old. It can be used in pregnant, breeding, and stud dogs. There is a beef flavor to the chewable, so other options would need to be considered in dogs with food allergies.


Nexgard     This oral monthly prevention is used in dogs to kill fleas and ticks. The main ingredient, afoxolaner, kills adult fleas within 24 hours, thereby preventing them from laying new eggs. It is also currently approved to kill the American Dog Tick, which transmits Rocky Mountain Spotted Fever, tularemia, Ehrlichiosis, and canine tick paralysis). The company that created the product is currently trying to get it approved to kill the other species of ticks. Since it is not a topical product, the efficacy is not decreased when dogs swim or are bathed within 2 days before or after application. The most common adverse reactions are mild, and they include vomiting, diarrhea, lethargy, dry skin and lack of appetite. The safety has not been evaluated in pregnant, breeding, or lactating dogs. Due to the rare risk of neurologic side effects, dogs with a history of seizures must be given this medication with caution. It can be given to puppies that are at least eight weeks old and weigh 4 pounds.


Sentinel     This monthly chewable tablet for dogs has two main ingredients: milbemycin oxime and lufenuron. Milbemycin acts to prevent heartworms as well as control and prevent hookworms, roundworms, and whipworms. Since this is a heartworm preventative, dogs over 7 months need to be tested prior to starting. Lufenuron is used to prevent and control flea infestations by preventing their eggs from developing into adults. It does not directly kill or repel adult fleas, so dogs can pick up an adult flea from infested environments (such as the dog park). In situations such as this, it would be necessary to give pets a product that kills adults, such as Capstar. Lufenuron is absorbed from the small intestines and stored in fat, which acts as a reservoir to slowly redistribute it into systemic circulation.
    Adverse effects are infrequent and can include vomiting, lethargy and diarrhea. If a pet is overdosed, weakness and neuroligic deficits can occur. To decrease the chances of side effects and to increase absorption, this medication must be given with food. This product does not offer tick protection, so if dogs are exposed to areas that potentially have ticks, it would be necessary to add another product.

Seresto Collar

Seresto Collar     This collar is used in both dogs and cats and contains two main ingredients, imidacloprid and flumethrin. Imidacloprid kills adult fleas and controls flea infestations. The adult fleas are killed before they can lay eggs, thereby decreasing the flea population. Flumethrin repels and kills Deer ticks (transmit Lyme disease and anaplasmosis), American dog ticks (transmit Rocky Mountain Spotted Fever and ehrlichiosis), Brown dog ticks (transmit ehrlichiosis, anaplasmosis, bartonellosis, canine hemoplasmosis, babesiosis, and Rocky Mountain Spotted fever), and Lone Star ticks (vector of ehrlichiosis). By repelling and killing ticks, they cannot attach and transmit disease.
    The Seresto collar slowly and continuously releases active ingredients over 8 months. In order for the collar to properly work, it must touch the skin and fur. Just like a regular collar, the Seresto collar should be fitted so two fingers can fit between the collar and pet's skin. It is water resistant, but only if pets are bathed once monthly. If pets swim once a month or more, the collar works for about five months. It can be applied to kittens at 10 weeks and dogs at 7 weeks.

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